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目的探讨急性冠脉综合征(ACS)患者介入治疗后与心室重构和心功能的相关性研究。方法47例ACS患者,依据术前cTnI的检测结果分为正常组25例和异常组22例,以手术前后LAD、LVD、IVS、LVPW、LVEF、E/A比值、cTnI作为观察指标,对上述指标进行统计学分析。结果与术前cTnI正常组相比,cTnI升高组的LAD、LVD显著增高(P<0.05),而IVS、LVPW、LVEF、E/A比值显著性降低(P<0.05);手术后cTnI含量与Lad、LVD呈独立正相关,与IVS、LVPW呈独立负相关。结论cTnI浓度与ACS患者术后心肌重构及心功能改变有显著的相关性,可能是独立危险因素。
Objective To investigate the relationship between ventricular remodeling and cardiac function after interventional therapy in patients with acute coronary syndrome (ACS). Methods 47 patients with ACS were divided into normal group (n = 25) and abnormal group (n = 22) according to preoperative cTnI test results. Before and after operation, LAD, LVD, IVS, LVPW, LVEF, E / A ratio and cTnI were used as observation indexes. Indicators for statistical analysis. Results Compared with the normal cTnI preoperative group, the LAD and LVD were significantly increased (P <0.05) and the IVS, LVPW, LVEF and E / A ratios were significantly decreased in the cTnI elevated group (P <0.05) It was independently and positively correlated with Lad, LVD and negatively correlated with IVS and LVPW. Conclusions There is a significant correlation between cTnI concentration and postoperative myocardial remodeling and cardiac function in patients with ACS, which may be an independent risk factor.