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过去10年,免疫学迅速渗透到医学的所有领域,为阐明人类许多疾病的发病机理做出了巨大贡献。移植物抗宿主病(GVHD)的识别,对人们了解淋巴细胞各亚群及其功能,移植及移植抗原、免疫遗传学、巨噬-淋巴细胞的相互作用以及免疫抑制机制等,提供了一个有用的、丰富人们知识的楷模。对人GVHD的认识是从骨髓移植中逐步发展起来的,但对输血引起这种反应的可能性研究甚少。近年来通过动物研究,人们将某些自身免疫和淋巴肿瘤性疾病与移植物抗宿主反应(G VHR)联系起来。人GVHD是人GVHR的临床表现。不能
In the past decade, immunology has rapidly penetrated into all areas of medicine and has made a significant contribution to elucidating the pathogenesis of many human diseases. The identification of graft versus host disease (GVHD) provides a useful guideline for understanding the subgroups of lymphocytes and their functions, transplantation and transplantation of antigens, immunological genetics, macrophage-lymphocyte interactions, and immunosuppressive mechanisms Enrich the model of people’s knowledge. The understanding of human GVHD is gradually evolved from bone marrow transplantation, but little is known about the potential for this response to transfusion. In recent years animal studies have linked some autoimmune and lymphomatous diseases to graft versus host response (G VHR). Human GVHD is a clinical manifestation of human GVHR. Can not