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在试管内使用数种酶,就可以把通过遗传已定型的人的血型(ABO 型)加以改变的划时代的实验,已在日本群马大学医学法医学教研室(古川研教授)获得成功。古川研教授等人根据人的红细胞的血型是由血球表面多糖类的构造所决定的这点出发,一直在进行使用具有能使这些糖结合或分离的特殊来人工改变血型的研究。例如,将 A 型血液转换成 B 型时,首先利用微生物生产的 A 型分解酶,从 A 型红细胞的表面分离持有的醣,使之暂且返回到 O 型红细胞。接着,使从人的唾液中提取的 B 型合成酶作用,与 B 型特有的糖结合,制造 B 型的红白细胞。
An epoch-making experiment that alters the blood type (ABO type) of genetically established humans using several enzymes in a test tube has been successful at the Faculty of Medical Forensics, Gunma University (Professor Furukawa). Based on the fact that the blood type of human erythrocytes is determined by the structure of the polysaccharide on the surface of the blood cell, Professor Furukawa et al. Have been studying the use of special, artificially altered blood types that can bind or separate these saccharides. For example, when the type A blood is converted into type B, the held sugar is first separated from the surface of the type A red blood cell by the use of the type A degrading enzyme produced by the microorganism and temporarily returned to the type 0 red blood cell. Next, type B synthase extracted from human saliva is combined with type B sugar to produce type B erythroblasts.