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目的观察氟桂利嗪和头痛宁治疗偏头痛的临床疗效。方法 120例偏头痛患者随机分为观察组和对照组各60例,对照组睡前口服氟桂利嗪胶囊,1粒/d,观察组在对照组基础上口服头痛宁胶囊,3粒/次,3次/d。两组均连续治疗28d。结果治疗后两组的疼痛程度有明显缓解,与治疗前比较差异有统计学意义(P<0.05)。治疗后两组比较差异有统计学意义(P<0.05)。治疗前观察组和对照的评分为(7.82±1.24)分和(7.91±1.15)分,两组比较差异无统计学意义(P>0.05),治疗后评分分别为(3.55±2.07)分和(4.67±1.86)分,与治疗前比较差异有统计学意义(P<0.05),治疗后比较差异也具有统计学意义(P<0.05)。观察组和对照组总有效率分别为95.0%和85.0%,差异有统计学意义(P<0.05)。结论氟桂利嗪和头痛宁治疗偏头痛临床疗效好,优于单纯西药治疗。
Objective To observe the clinical efficacy of flunarizine and taoitongning in the treatment of migraine. Methods One hundred and twenty migraineurs were randomly divided into observation group (60 cases) and control group (n = 60). The control group was treated with flunarizine capsules before bedtime (1 capsule per day), and the observation group was given Tongtongning capsules , 3 times / d. Two groups were treated for 28 days. Results After treatment, the pain of the two groups was significantly relieved, with significant difference compared with that before treatment (P <0.05). After treatment, the difference between the two groups was statistically significant (P <0.05). Before treatment, the scores of the observation group and the control group were (7.82 ± 1.24) points and (7.91 ± 1.15) points respectively, with no significant difference between the two groups (P> 0.05). After treatment, the scores were (3.55 ± 2.07) and 4.67 ± 1.86), respectively. The difference was statistically significant (P <0.05) before treatment and after treatment, the difference was also statistically significant (P <0.05). The total effective rate in observation group and control group was 95.0% and 85.0%, respectively, with significant difference (P <0.05). Conclusion Flunarizine and Touttongning are effective in treating migraine with better clinical curative effect than western medicine alone.