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目的:观察二丁酰环磷腺苷钙联合丹红注射液对冠心病不稳定性心绞痛患者的临床疗效。方法:选取冠心病不稳定性心绞痛患者306例,随机分成三组,均以常规西药治疗为基础;A组应用二丁酰环磷腺苷钙联合丹红注射液,B组应用二丁酰环磷腺苷钙,C组应用丹红注射液;14d为一疗程。结果:三组血清hs-CRP、NT-proBNP水平均比治疗前明显降低(P<0.05);并且A组表达较B、C组明显降低(F=20.929,P<0.001;F=5.888,P=0.003)。结论:二丁酰环磷腺苷钙联合丹红注射液缓解UAP心绞痛的发作、心电图缺血改变及心功能的恶变,并能降低血清hs-CRP、NT-proBNP水平。
Objective: To observe the clinical efficacy of calcium biliary adenosine monophosphate combined with Danhong injection in patients with coronary heart disease and unstable angina pectoris. Methods: A total of 306 patients with coronary heart disease with unstable angina pectoris were randomly divided into three groups, all of which were based on conventional western medicine. Group A was given calcium butyrate cidofused calcium together with Danhong injection, and group B was treated with calcium butyrate cyclic adenosine monophosphate , C group Danhong injection; 14d for a course of treatment. Results: The serum levels of hs-CRP and NT-proBNP in three groups were significantly lower than those before treatment (P <0.05), and the expression of serum hs-CRP and NT-proBNP in group A were significantly lower than those in group B and C (F = 20.929, = 0.003). CONCLUSION: Calcium dibutyryl adenosine monophosphate combined with Danhong injection can relieve the occurrence of UAP angina pectoris, ischemic changes of electrocardiogram and malignant cardiac function, and reduce the levels of serum hs-CRP and NT-proBNP.