目前磁共振图象已成为一种重要的诊断工具,因此人们广泛寻找提高图象精度的方法。为了减少顺磁离子Gd~(3+)、Mn~(2+)、Fe~(3+)的毒性,延长血液滞留时间,质子弛豫时间增加,以便提高磁共振图象精度,本文研究了用脂质体作为顺磁离子载体的络合载体理化性质、稳定性、大鼠体内药动学、器官分布以及磁共振图象。脂质体的组成为豆磷脂、胆固醇及亲脂螯 The current magnetic resonance imaging has become an important diagnostic tool, so people are looking for ways to improve the accuracy of the image. In order to reduce the toxicity of paramagnetic ions Gd ~ (3 +), Mn ~ (2 +) and Fe ~ (3+), prolong the residence time of blood and increase the proton relaxation time in order to improve the magnetic resonance imaging accuracy, Physical and Chemical Properties, Stability, Pharmacokinetics, Organ Distribution, and Magnetic Resonance Imaging of Complex Carriers with Liposomes as Paramagnetic Ionophores. The composition of liposomes is soya lecithin, cholesterol and lipophilic chelates