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目的:建立复方硫酸软膏素滴眼液中硫酸软骨素三种含量测定方法。方法:分别采用络合滴定法、染色法、氧瓶燃烧法检测复方硫酸软膏素滴眼液中的硫酸软骨素的含量。结果:三种方法均可排除滴眼液中玻璃酸钠的干扰,准确地检测硫酸软骨素的含量。结论:所述三种检测方法可行性较高。
Objective: To establish a method for the determination of three contents of chondroitin sulfate in Compound Sulfate Ointment Eye Drops. Methods: The contents of chondroitin sulfate in Compound Sulfate Ointment Eye Drops were detected by complexometric titration, staining and oxygen flask combustion respectively. Results: All the three methods could eliminate the interference of sodium hyaluronate in the eye drops and accurately detect the content of chondroitin sulfate. Conclusion: The three detection methods are more feasible.