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目的:观察中西医结合治疗卵巢早衰的临床疗效。方法:将152例卵巢早衰患者随机分为3组。中西医结合治疗组(中西医结合组)58例,采用抗卵衰冲剂与人工周期方案治疗,人工周期对照组(人工周期组)58例,仅用西药人工周期方案治疗,抗卵衰冲剂对照组(中药组)36例,仅采用抗卵衰冲剂治疗,3组疗程均为3个月。结果:3组疗效间差异有统计学意义(P<0.01)。3组患者血促卵泡激素(FSH)、促黄体生长素(LH)、血清雌二醇(E2)治疗前差异均无统计学意义(P>0.05),3组患者治疗后FSH、E2间差异均有统计学意义(P<0.05);但3组治疗后血清LH间差异无统计学意义(P>0.05)。3组患者均无明显不良反应。结论:抗卵衰冲剂联合人工周期方案治疗卵巢早衰疗效确切、起效快。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of premature ovarian failure. Methods: 152 cases of premature ovarian failure were randomly divided into three groups. Fifty-eight patients with Integrative Medicine (TCM-WM) group were treated with anti-ovulation decoction and artificial cycle regimen. Fifty-eight patients in the artificial cycle group (artificial cycle group) Group (Chinese medicine group) 36 cases, only the use of anti-ovarian follicle treatment, three courses were 3 months. Results: The difference between the three groups was statistically significant (P <0.01). There were no significant differences in FSH, LH and E2 between the three groups before treatment (P> 0.05). The difference of FSH and E2 between the three groups after treatment (P <0.05). However, there was no significant difference between the three groups in serum LH after treatment (P> 0.05). No significant adverse reactions in 3 groups of patients. Conclusion: The anti-ovarian failure granules combined with artificial cycle regimen for the treatment of premature ovarian failure curative effect is rapid, rapid onset.