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Ⅰ型变应反应与黄芩黄芩的主要成分有黄芩甙与黄芩色素,它能明显抑制Ⅰ型变应反应。其主要作用与色甘酸二钠相同,能抑制 IgE 抗体所引起的致敏肥大细胞的脱粒现象和介质游离作用。与黄芩色素抑制 IgE 抗体、IgG 所致反应不同的是,色甘酸二钠只能抑制 IgE 抗体所致的反应,而不能抑制 IgG 抗体所引起的反应。由于两者结构极为相似,因此引导出了两种抗体的功能部位有区别的假说,并取得了 BPS 这一化合物。将黄芩色素与 BPS进行临床实验时.发现用50%BPS 软膏治疗的27例特应性皮炎中,有25例有显著疗效。Ⅳ型变应反应与柴补汤、厚朴、半夏柴朴汤有抑制Ⅰ型,Ⅳ型变应反应的作用。其作用系周期效应,并有增加类固醇的作用。与类固醇的区别是不能抑制诱导期。这一周期效应是 T 细胞受抗原刺激后,使皮肤反应因子、游走抑制因子或单细胞趋
The main components of type I allergic reactions and Astragalus membranaceus are Astragalus membranaceus and Astragalus membranaceus pigments, which can significantly inhibit type I allergic reactions. Its main function is the same as that of disodium cromoglycate, which can inhibit the degranulation phenomenon and media free action of sensitized mast cells caused by IgE antibodies. Different from the reaction caused by Scutellaria Pigment Inhibition of IgE antibody and IgG, disodium cromoglycate can only inhibit the reaction caused by IgE antibody but not the reaction caused by IgG antibody. Because the two structures are very similar, they led to the hypothesis that the functional sites of the two antibodies differ, and obtained the BPS compound. When clinical trials were conducted between Astragalus pigment and BPS, 25 out of 27 atopic dermatitis treated with 50% BPS ointment were found to have significant efficacy. Type IV allergic reactions and Chaibu Decoction, Magnolia Officinalis, and Banxia Chai Pu Decoction can inhibit type I and type IV allergic reactions. Its role is a cyclic effect, and there is an increase in steroids. The difference with steroids is that it does not inhibit the induction period. This cyclical effect is caused by T cell stimulation by antigens that causes skin response factors, migration inhibitory factors, or single-cell tropism.