研究阻断新生血管的形成,是减少和预防肿瘤转移,进行肿瘤治疗的新策略。血管形成是由多种因子激发和调控的,其中,血管内皮细胞生长因子(VEGF)是目前发现的最为强大和专一的刺激内皮细胞增生的因子。VEGF 是一种糖蛋白,由2个分子质量为17～22 ku 相同的亚基经过二硫键连接形成分子质量为34～35 ku 的同源二聚体。人 Research blocking the formation of new blood vessels, is to reduce and prevent tumor metastasis, a new strategy for cancer treatment. Vascular formation is stimulated and regulated by a variety of factors, of which vascular endothelial growth factor (VEGF) is the most powerful and specific factor currently found to stimulate endothelial proliferation. VEGF is a glycoprotein consisting of two homoduplexes of the same molecular mass from 17 to 22 ku linked via disulfide bonds to form homodimers 34 to 35 ku in molecular mass. people