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目的探讨无功能胰岛细胞瘤的诊断治疗。方法对近17年间湘雅医院收治的29例无功能胰岛细胞瘤患者的临床资料进行回顾性分析。结果 29例患者均无明显临床症状,最常见的临床体征为腹部包块(25/29)。B超和CT为最常用的术前检查手段,其阳性率分别为100%(29/29)和96.5%(28/29)。其中良性占65.5%(19/29),恶性占34.5%(10/29)。手术切除率为100%。结论无功能胰岛细胞瘤症状缺乏特异性,B超及CT应为首选的检查方法。包膜不完整和浸润性生长者可确诊为恶性,外科手术是首选方法,疗效优于胰腺外分泌肿瘤。
Objective To investigate the diagnosis and treatment of non-functional islet cell tumor. Methods The clinical data of 29 patients with non-functioning islet cell tumor admitted to Xiangya Hospital during the past 17 years were retrospectively analyzed. Results All the 29 patients had no obvious clinical symptoms. The most common clinical signs were abdominal mass (25/29). B-ultrasound and CT were the most commonly used methods of preoperative examination. The positive rates were 100% (29/29) and 96.5% (28/29) respectively. Among them, 65.5% (19/29) were benign and 34.5% (10/29) were malignant. Surgical resection rate was 100%. Conclusion The symptoms of non-functioning islet cell tumor are lack of specificity. B-mode ultrasonography and CT should be the first choice of examination. Incomplete capsule and invasive growth may be diagnosed as malignant, surgery is the preferred method, the effect is superior to pancreatic exocrine tumors.