目的 :了解临沧地区支原体感染患者对多种抗生素的耐药情况,确定临床治疗的理论基础。方法 :以KB法对266例标本进行解脲支原体及人型支原体培养测试,开展药敏试验。结果:所有参加化验的标本支原体呈现阳性的数量为122,感染率为45.9%,解脲支原体阳性数量为101例,而两种支原体合并的数量为14例。人型支原体阳性7例,解脲支原体阳性对左氧沙星耐药率最高,均为72.3%。单一人型支原体阳性对红霉素和阿齐霉素耐药率最高,均为85.7%。解脲支原体合并人型支原体阳性对左氧沙星和红霉素耐药率最高,均为85.7%。结论 :基于临床上对抗生素的滥用是的解脲支原体与人型支原体的耐药菌株数量激增。尤其引起的泌尿生殖系统感染也呈逐年增多趋势。因此通过对支原体药物敏感情况的测试分析可以促进对支原体流行情况及耐药程度的研究深入,指导临床合理用药,提高治疗效果及减少耐药性有重要的参考意义 Objective: To understand the resistance of patients with mycoplasma infection in a variety of antibiotics in Lincang area and to determine the theoretical basis of clinical treatment. Methods: KB method for 266 specimens of Ureaplasma urealyticum and Mycoplasma hominis culture test to carry out drug susceptibility testing. Results: All specimens tested positive for Mycoplasma pneumoniae were 122, the infection rate was 45.9%, the positive number of Ureaplasma urealyticum was 101 and the number of the two mycoplasma was 14. Mycoplasma hominis positive in 7 cases, Ureaplasma urealyticum positive levofloxacin resistant rate was the highest, were 72.3%. The positive rate of single mycoplasma-positive erythromycin and azithromycin was the highest, both 85.7%. Ureaplasma urealyticum combined with Mycoplasma hominis-positive levofloxacin and erythromycin-resistant rates were the highest, were 85.7%. Conclusions: The number of drug-resistant strains of UU and Mycoplasma hominis is rapidly increasing based on the clinical abuse of antibiotics. In particular, genitourinary infections are also increasing year by year. Therefore, through the mycoplasma drug sensitivity test analysis can promote the prevalence of Mycoplasma and drug resistance in-depth study, to guide clinical rational use of drugs to improve the therapeutic effect and reduce resistance has important reference value