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目的:探讨睾丸粘膜相关组织(MALT)淋巴瘤的临床病理特征,为临床早期诊断提供依据。方法:对4例睾丸MALT淋巴瘤作临床病理观察,同时采用S-P法或ABC法进行LCA、L26、UCHL1、Bcl-2免疫组化标记。结果:患者临床症状为睾丸不同程度肿大。组织学图象与胃肠道MALT淋巴瘤相似,1例转化为高度恶性MALT淋巴瘤。免疫组化结果显示瘤细胞表达LCA、L26和Bcl-2。结论:老年人出现睾丸弥漫性肿大,首先应考虑睾丸淋巴瘤的可能。该病的确诊依赖病理诊断,免疫组化对于鉴别诊断有重要作用
Objective: To investigate the clinicopathological features of testicular mucosa-associated tissue (MALT) lymphoma and provide the basis for early clinical diagnosis. Methods: Four cases of testicular MALT lymphoma were observed clinically and pathologically. LCA, L26, UCHL1 and Bcl-2 were immunohistochemically labeled by S-P method or ABC method. Results: The clinical symptoms of patients with varying degrees of testicular swelling. Histologic images were similar to gastrointestinal MALT lymphoma, with 1 translating into a highly malignant MALT lymphoma. Immunohistochemistry showed that the tumor cells expressed LCA, L26 and Bcl-2. Conclusion: The elderly appear diffuse testicular enlargement, the possibility of testicular lymphoma should be considered first. The diagnosis of the disease depends on pathological diagnosis, immunohistochemistry for differential diagnosis has an important role