蠕虫感染的流行和对社会经济的影响,仍然是目前全球关心的问题。本文例举了重要的人体蠕虫感染在全球包括印度各地流行的情况,并对大量抗蠕虫药的应用和药理学及临床特征做了评论。作者认为抗蠕虫药的发展已取得了很大进展,建立了大量有用的初筛和复筛模型。实验模型的选择应尽可能在分类学、生活史、致 The prevalence and socio-economic impact of the worm infection remains the current global concern. This article gives an account of the prevalence of important human helminth infections throughout the world, including in India, and comments on the application and pharmacological and clinical features of a large number of anthelmintic drugs. The author believes that anthelmintics have made great progress in the development and established a large number of useful primary screening and re-screening models. The choice of experimental model should be as much as possible in taxonomy, life history, induced