肝纤维化是肝脏对各种原因所致慢性肝损伤的过度修复反应 ,是肝硬化形成的基础 ,如何有效治疗肝纤维化仍是肝病领域一个巨大挑战 ,本文扼要介绍其近年研究进展。1　去除病因如戒酒、慢性病毒性肝炎的抗病毒治疗、去除铁或铜超载、解除机械性胆道阻塞等 ,是目前最有效的措施 ,可 Hepatic fibrosis is an overrecovery reaction of chronic liver injury caused by various reasons in the liver and is the basis of the formation of cirrhosis. How to effectively treat liver fibrosis is still a huge challenge in the field of liver disease. This article briefly introduces the research progress in recent years. 1 to remove the cause, such as alcohol, chronic viral hepatitis antiviral therapy, removal of iron or copper overload, lifting of mechanical biliary obstruction, is the most effective measures, may