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[目的] 观察萎胃冲剂对大鼠慢性萎缩性胃炎(CAG)的治疗作用。[方法] 以自研中药萎胃冲剂对脱氧胆酸造模的复合型CAG大鼠进行治疗,观察其体重、胃液酸度及胃蛋白酶活性,胃黏膜组织病理变化等方面的作用,并以胃苏冲剂作对照。[结果] 萎胃冲剂可增加造模大鼠的体重,提高其降低的胃液酸度和胃蛋白酶活性,改善其胃黏膜组织的病理变化,效果明显优于胃苏冲剂。[结论] 萎胃冲剂对大鼠CAG具有良好的治疗作用。
[Objective] To observe the therapeutic effect of Weiwei Granules on chronic atrophic gastritis (CAG) in rats. [Method] The compound CAG rats modeled by deoxycholic acid were treated with the self-researched Chinese medicine Weiwei granules. The body weight, gastric acidity, pepsin activity, histopathological changes of gastric mucosa were observed, and the effects were observed. Granules as a control. [Results] Weiwei granules can increase the body weight of model rats, increase their decreased gastric acidity and pepsin activity, and improve the pathological changes of their gastric mucosal tissues. The effect is significantly better than Weisu granules. [Conclusion] Weiwei granule has a good therapeutic effect on rat CAG.