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目的临床研究利用胰岛素强化治疗初发2型糖尿病的治疗效果。方法本文病例均选取笔者所在科室2011年3月至2012年4月间收治的46例初发2型糖尿病患者临床资料进行回顾分析。结果两组患者的血糖达标时间及胰岛素用量情况差异无显著性;两组患者的糖化血红蛋白、三酰甘油、空腹血糖和餐后2h的血糖值均有所下降,而体重变化指数方面无显著性,P均﹥0.05。结论采用两种不同胰岛素强化治疗方案治疗初发2型糖尿病,其疗效均较为显著,可有效改善葡萄糖毒性以及β细胞功能,安全性较高,因而均值得临床推广应用。
Objective To study the clinical effect of intensive insulin therapy on type 2 diabetes mellitus. Methods The cases were selected in my department from March 2011 to April 2012 46 cases of newly diagnosed type 2 diabetes mellitus were retrospectively analyzed. Results There was no significant difference between the two groups in blood glucose up-time and insulin dosage. The levels of HbA1c, triglyceride, fasting blood glucose and postprandial blood glucose in two groups were decreased, but no significant changes in body weight index , P> 0.05. Conclusion Two kinds of intensive insulin therapy for the treatment of newly diagnosed type 2 diabetes mellitus have obvious curative effect, which can effectively improve the glucose toxicity and β-cell function and have higher safety. Therefore, it is worthy of clinical application.