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目的探讨药物流产后机体生殖激素水平与子宫异常出血的相关性。方法选取药流后子宫出血小于16d者为正常组,子宫出血大于16 d者为异常组,手术流产妇女为对照组。连续监测三组妇女流产10~22 d的E2、P、FSH、LH、HCG水平。结果三组E2水平变化基本相同,呈上升趋势;异常组P水平始终显著高于对照组和正常组(P<0.05);三组FSH水平均在反复波动,LH水平呈下降趋势;异常组HCG水平始终显著高于对照组和正常组(P<0.05)。结论药物流产后子宫异常出血与高水平的P和HCG有关,而与E2、LH、FSH无关。
Objective To investigate the correlation between reproductive hormone levels and abnormal uterine bleeding after medical abortion. Methods: The uterine bleeding less than 16 days after medical abortion was selected as the normal group, the uterine bleeding more than 16 days was the abnormal group, and the surgical abortion women as the control group. The levels of E2, P, FSH, LH and HCG in 10-22 days of abortion in three groups were continuously monitored. Results The levels of E2 in the three groups were basically the same and showed an upward trend. The levels of P in the abnormal group were always significantly higher than those in the control group and the normal group (P <0.05). The levels of FSH in the three groups fluctuated repeatedly and the LH level decreased. The level was always significantly higher than the control group and the normal group (P <0.05). Conclusion Abnormal uterine bleeding after medical abortion is associated with high levels of P and HCG, but not with E2, LH and FSH.