目的:探讨妊娠期高血压疾病患者内脂素水平与新生儿体重的相关性。方法:选取2009年1月~2012年12月在延边大学附属医院住院分娩的单胎妊娠妇女89例,其中妊娠期高血压疾病妇女43例为A组,正常妊娠妇女46例为B组,测定两组产妇的内脂素、血脂和尿酸(UA)水平,并分析影响新生儿体重的因素。结果:A组总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、UA、内脂素水平均高于B组,而新生儿出生体重低于B组,差异均有统计学意义(P<0.05)。结论:妊娠期高血压疾病和高UA血症是影响新生儿出生体重的因素。妊娠期预防血压和UA的升高,对妊娠妇女的健康及胎儿的生长发育具有重要的意义。 Objective: To investigate the correlation between the level of visfatin and neonatal body weight in patients with gestational hypertension. Methods: A total of 89 singleton pregnant women delivered in hospital of Yanbian University from January 2009 to December 2012 were selected. Among them, 43 women with gestational hypertension were Group A, 46 women with normal pregnancy were Group B, The two groups of maternal visfinoid, lipids and uric acid (UA) levels, and analysis of factors affecting the newborn weight. Results: The levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), UA and visfatin in group A were higher than those in group B, while the birth weight of newborns was lower than that in group B Statistical significance (P <0.05). Conclusion: Hypertensive disorders and hyperuricemia in pregnancy are the factors influencing newborn birth weight. Preventive blood pressure and UA during pregnancy increase the health of pregnant women and fetal growth and development of great significance.