论文部分内容阅读
目的建立基于傅里叶变换红外光谱(FTIR)、气相色谱-质谱(GC-MS)结合高分辨质谱技术联合鉴定未知样品的方法。方法未知样品采用红外专用取样器直接检测;甲醇溶解后采用GC-MS和组合型高分辨质谱检测,以MDMA为内标物。结果未知样品获得的红外光谱特征吸收峰为1 679(C=O键),1603,1502,1453,1423,1259,1121,1090,1035,930,887,838,768,742和717cm-1,质谱特征碎片峰(m/z)为58.1,91.0,120.9,149.0和207.0,测得的精确质量数[M+H]+为208.0966。经信息分析未知样品鉴定为3,4-亚甲二氧基甲卡西酮,该物质属于新型化学合成卡西酮类精神活性物质,已经列入部分欧盟国家的管制药物目录。结论本方法可用于3,4-亚甲二氧基甲卡西酮的鉴定。
Objective To establish a method for the identification of unknown samples based on Fourier transform infrared spectroscopy (FTIR) and gas chromatography-mass spectrometry (GC-MS) combined with high resolution mass spectrometry. Methods Unknown samples were directly detected by infrared special sampler. Methanol was detected by GC-MS and combined high-resolution mass spectrometry with MDMA as internal standard. Results The peaks of infrared spectra obtained by unknown samples were 1679 (C = O bond), 1603,1502,1453,1423,1259,1121,1090,1035,930,887,838,768,742 and 717cm-1, ) Of 58.1, 91.0, 120.9, 149.0 and 207.0. The exact mass number [M + H] + was found to be 208.0966. The information analysis of unknown samples identified as 3,4 - methylenedioxymetacetone, a new type of chemical synthesis of cathinics psychoactive substances, has been included in the list of controlled drugs in some EU countries. Conclusion This method can be used to identify 3,4-methylenedioxymetazidine.