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众所周知,大面积烧伤救治的重要环节是能否预防和控制烧伤感染的发生与发展。1964年Teplitz和Moncrief等提出烧伤创面脓毒症的概念后,医学界对局部抗感染药物的研究日益重视,新的烧伤创面治疗剂不断出现。碘于1839年开始用作防腐消毒药,由于其效果确切而沿用至今,但由于碘不溶于水,且有刺激性和一定毒性,使其应用受限。1953年由聚烯吡酮和碘结合而成的伏碘(Betadine)被证明为水溶性,刺激轻,毒性极小后,很快被用于临床。国外1956年始用于烧伤治疗。在国内,1985年上海瑞金医院报道了应用伏碘洗手消毒的经验,但
As we all know, an important part of large-scale burn treatment is whether prevention and control of the occurrence and development of burn infection. After Teplitz and Moncrief proposed the concept of burn wound sepsis in 1964, the medical profession has paid more and more attention to the study of topical anti-infective drugs. New therapeutic agents for burn wounds continue to emerge. Iodine began to be used as antiseptic disinfectant in 1839, and its use has been still used due to its exact effect. However, its application is limited because iodine is insoluble in water and has irritant and certain toxicity. Betadine, a combination of povidone and iodine in 1953, proved to be water-soluble, light-stimulated and extremely toxic, and was rapidly used clinically. Foreign 1956 for burn treatment. In China, Shanghai Ruijin Hospital in 1985 reported the application of disinfection iodophors handwashing experience, however