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目的观察腺苷蛋氨酸治疗淤胆型肝炎的临床疗效。方法将我科收治的80例淤胆型肝炎患者随机分为两组,对照组给予复方甘草酸苷、还原型谷胱甘肽、维生素C、肌苷等保肝治疗。治疗组在保肝基础上加用腺苷蛋氨酸1000mg加入5%葡萄糖250ml中,静脉滴注,1次/d,两组疗程均为4周。结果治疗结束后,治疗组总有效率高于对照组(P<0.05);治疗组治疗后TBIL、ALT、GGT、AKP均明显低于治疗前(P<0.05)。结论腺苷蛋氨酸治疗淤胆型肝炎疗效好。
Objective To observe the clinical efficacy of adenosine methionine in the treatment of cholestatic hepatitis. Methods 80 patients with cholestatic hepatitis treated in our department were randomly divided into two groups. The control group was given compound glycyrrhizin, reduced glutathione, vitamin C, inosine and other hepatoprotective drugs. In the treatment group, adenosine methionine (1000mg) was added to 250ml of 5% glucose on the basis of liver protection. The patients in the treatment group received intravenous infusion once a day for 4 weeks. Results After treatment, the total effective rate of the treatment group was higher than that of the control group (P <0.05). The TBIL, ALT, GGT and AKP in the treatment group were significantly lower than those before treatment (P <0.05). Conclusions Adenosine methionine is effective in treating cholestatic hepatitis.