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目的探讨甲状腺Ⅰ类切口手术围术期预防性使用抗菌药物的效果。方法回顾性选取2013年8月至2014年8月于军埠镇卫生院行甲状腺手术的甲状腺Ⅰ类切口患者196例作为对照组,以2014年9月至2015年9月甲状腺Ⅰ类切口手术患者204例作为研究组,研究组患者采用预防性抗菌药物的相关干预措施,比较两组患者围术期抗菌药物使用率、药物使用的合理性及住院费用等。结果研究组患者围术期预防性的抗菌药物使用率为51.0%,明显低于对照组的97.4%;在抗菌药物的使用适应证、抗菌药物联合使用及药物种类选择方面,研究组患者的抗菌药物使用合理性明显高于对照组,住院费用明显低于对照组,差异均有统计学意义(均P<0.05)。结论通过对甲状腺Ⅰ类切口手术的抗菌药物预防性使用进行相关干预措施,规范抗菌药物使用管理,避免加强病原菌的耐药性,临床效果显著,能够明显降低抗菌药物使用率,提高抗菌药物的使用合理性,同时降低了住院费用。
Objective To investigate the effect of perioperative prophylactic use of antimicrobial agents in type Ⅰ thyroidectomy. Methods A retrospective study was conducted between 196 patients with thyroid Ⅰ-type incision undergoing thyroidectomy in Junbu Town Health Center from August 2013 to August 2014. The patients underwent thyroidectomy for type Ⅰ Ⅰ incision from September 2014 to September 2015 204 cases as the research group, the study group of patients with preventive antibacterial interventions, compared the two groups of patients perioperative antibacterial drug use, the rational use of drugs and hospitalization costs. Results The perioperative prophylactic antimicrobial use rate in study group was 51.0%, which was significantly lower than that in control group (97.4%). In terms of the use of antimicrobial agents, combination of antimicrobial agents and choice of drugs, The rationality of drug use was significantly higher than that of the control group, and the hospitalization cost was significantly lower than that of the control group (all P <0.05). Conclusions Through preventive interventions on the preventive use of antimicrobial agents for thyroid type Ⅰ incision surgery, the administration of antimicrobial agents is regulated and the drug resistance of pathogens is not strengthened. The clinical effect is significant, which can significantly reduce the usage of antimicrobial agents and enhance the use of antimicrobial agents Reasonable, while reducing hospital costs.