取代吡唑酰基异硫氰酸酯与杂环胺、磺酰胺反应 ,得到了加成产物取代吡唑酰基硫脲或关环产物吡唑并 [4 ,5- e][1,3]噻嗪。取代吡唑酰基硫脲化合物在三乙胺作用下也关环成吡唑并 [4 ,5- e][1,3]噻嗪。化合物结构均经 1HNMR、IR及元素分析确证 ,并对此加成、环化反应结果和机理进行了讨论。初步生物活性测试表明 ,这些化合物具有一定的杀菌、除草和植物生长调节作用 The substituted pyrazole acyl isothiocyanate is reacted with the heterocyclic amine and the sulfonamide to obtain the addition product substituted pyrazolylthiourea or the ring-closing product pyrazolo [4,5-e] [1,3] thiazine . Substituted pyrazoylthiourea compounds are also cyclized to pyrazolo [4,5-e] [1,3] thiazines under the action of triethylamine. The structures of the compounds were confirmed by 1HNMR, IR and elemental analysis. The addition and cyclization reaction results and mechanism were also discussed. Preliminary biological activity tests show that these compounds have some bactericidal, herbicidal and plant growth regulating effects