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研究证实姜黄素和儿茶素两种成分体外单独应用均可抑制大肠癌细胞的生长并诱导其凋亡。体内研究已证实姜黄素和儿茶素两种天然化合物的联合应用具有良好的预防大鼠大肠癌发生的作用,其作用机制可能是通过抑制隐窝异常病灶(aberrant crypt foci,ACF)的形成实现的。本实验旨在探讨由姜黄素联合儿茶素对二甲基肼(DMH)诱导大
Studies have shown that both curcumin and catechin alone can inhibit the growth of human colorectal cancer cells and induce their apoptosis in vitro. In vivo studies have shown that the combination of curcumin and catechin has a good effect on prevention of colorectal cancer in rats. The mechanism may be through inhibiting the formation of aberrant crypt foci (ACF) of. The purpose of this experiment was to investigate the induction of dimethylhydrazine (DMH) by curcumin in combination with catechin