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目的分析研究小儿癫痫患者通过托吡酯片单药进行治疗的方法、治疗效果以及预后,为临床治疗提供依据。方法选取2012年9月至2014年9月收治的76例小儿癫痫患者的临床资料实施回顾性分析,将76例患者随机分为两组,观察组38例,对照组38例,对照组患者此前服用过其他抗癫痫药物,在此基础之上辅助使用托吡酯片加以治疗,观察组患者未服用过抗癫痫药物,仅使用托吡酯片加以治疗,比较观察组和对照组患者的治疗效果以及预后情况,将结果进行统计学分析。结果通过治疗之后,观察组患者治疗有效率显著高于对照组患者,差异有统计学意义(P<0.05);观察组患者出现不良反应的概率显著低于对照组患者,差异有统计学意义(P<0.05)。结论针对小儿癫痫患者使用托吡酯片单药进行治疗效果明显,患者出现不良反应概率小,可在临床中大力推广使用。
Objective To analyze the method, the therapeutic effect and the prognosis of pediatric epilepsy patients treated with topiramate tablets, and provide the basis for clinical treatment. Methods The clinical data of 76 pediatric patients with epilepsy admitted from September 2012 to September 2014 were retrospectively analyzed. 76 patients were randomly divided into two groups: observation group 38 cases, control group 38 cases, control group before Taking other antiepileptic drugs, on this basis, the auxiliary use of topiramate tablets to be treated, the observation group patients not taking antiepileptic drugs, only the use of topiramate tablets to be treated, the treatment group compared with the control group and the prognosis of patients, The results for statistical analysis. Results After treatment, the treatment efficiency in the observation group was significantly higher than that in the control group (P <0.05); the probability of adverse reactions in the observation group was significantly lower than that in the control group (the difference was statistically significant (P < P <0.05). Conclusion The treatment of pediatric epilepsy patients with topiramate tablets is effective, the patients have a small probability of adverse reactions, which can be widely used in clinical practice.