目的与方法：采用四氯化碳（ＣＣｌ４）诱导的大鼠慢性肝损伤的模型，观察肝炎平对大鼠血清ＡＬＴ、ＡＳＴ的活性及γ球蛋白含量的影响及其对慢性肝损伤的保护作用。结果：结果表明：肝炎平组血清ＡＬＴ活性为１０２０７±１５０２ｕ／Ｌ、ＡＳＴ为９３０１±２４０８ｕ／Ｌ，γ球蛋白含量为０２０３±００１３，模型组的血清ＡＬＴ、ＡＳＴ活性及γ球蛋白含量分别为１４７０５±１４０３、１３５０６±３７４及０２４３±００２６。Ｐ＜００１。肝组织中胶原增生的总面积肝炎平组为９２９０１±１６５５，面积百分数为５７３±１１１。而模型组胶原增生的总面积则为１６０１５５±２８１８５，面积百分数是９１９±１６７，Ｐ＜００１。结论：肝炎平能减轻肝细胞的损伤，抑制胶原的增生，有防治肝纤维化的作用。 Objective and Method: To observe the effect of Heyanping on the activity of serum ALT, AST and the content of γ-globulin in rats induced by chronic liver injury induced by carbon tetrachloride (CCl4) and its protective effect on chronic liver injury. . Results: The results showed that the serum ALT activity in Heyanping group was 10207±1502u/L, the AST was 9301±2408u/L, and the content of γ-globulin was 0203±0013. Serum ALT, AST activity and γ-globulin content were 14705±1403, 13506±374 and 0243±0026, respectively. P<001. The total area of ​​collagen hyperplasia in liver tissue was 92901±1655, and the area percentage was 573±111. The total area of ​​collagen hyperplasia in the model group was 160155±28185, and the area percentage was 919±167, P<001. Conclusion: Hepatitis can reduce the damage of liver cells, inhibit the proliferation of collagen, and prevent and treat hepatic fibrosis.