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[目的]探讨复方猴头胶囊联合泮托拉唑治疗糜烂性胃炎的临床疗效。[方法]收集我院门诊360例糜烂性胃炎患者的临床资料,分为HP(幽门螺杆菌)阳性治疗组(110例)及HP阳性对照组(106例)(随机分配);HP阴性治疗组(72例)及HP阴性对照组(72例)(随机分配)。阳性组先抗幽门螺杆菌治疗。治疗组予复方猴头胶囊联合泮托拉唑治疗,对照组予铝碳酸镁联合泮托拉唑治疗,对4组患者的治疗效果进行评价。[结果]不管是阳性组还是阴性组,治疗组与对照组的临床总有效率都很好(阳性组有效率分别是94.5%、93.4%;阴性组有效率分别是95.8%、95.8%),差异无统计学意义(P>0.05);但是对于大便次数增多的糜烂性胃炎患者,治疗组效果均优于对照组(阳性组有效率分别是93.3%、84.6%;阴性组有效率分别是90.5%、81.8%),差异有统计学意义(P<0.005)。[结论]复方猴头胶囊联合泮托拉唑治疗糜烂性胃炎效果好,特别对大便次数增多的患者获益更明显。
[Objective] To investigate the clinical efficacy of compound Herbal Capsules combined with pantoprazole in the treatment of erosive gastritis. [Methods] The clinical data of 360 patients with erosive gastritis from outpatient department of our hospital were collected and divided into HP (110 cases) and HP positive control group (106 cases) (random distribution); HP negative treatment group (72 cases) and HP negative control group (72 cases) (randomized). Positive group first anti-Helicobacter pylori treatment. The treatment group was treated with compound Herba capsules combined with pantoprazole, while the control group was treated with magnesium aluminum carbonate combined with pantoprazole to evaluate the therapeutic effect of the four groups of patients. [Results] The total effective rate of the treatment group and the control group was good (94.5% for the positive group, 93.4% for the positive group, 95.8% for the negative group, and 95.8% for the negative group, respectively) in both positive and negative groups. The difference was not statistically significant (P> 0.05), but for erosive gastritis patients with increased stool frequency, the effect of the treatment group was better than that of the control group (the effective rates of the positive group were 93.3% and 84.6%, respectively; %, 81.8%), the difference was statistically significant (P <0.005). [Conclusion] The compound Hericum capsule combined with pantoprazole is effective in treating erosive gastritis, especially for patients with increased stool frequency.