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在这项研究中 ,作者评估了乙型脑炎病毒 ( JEV)结构和非结构蛋白诱导保护性免疫反应的作用 ,并与用灭活 JEV疫苗免疫的结果相比较。用编码 JEV膜蛋白质粒 ( PE)免疫的一些近系杂交和远系杂交鼠能高度地保护致死性 JEV的攻击 ,其保护效果与用灭活疫苗获得的保护类似。然而所有其
In this study, the authors evaluated the role of JEV structure and nonstructural proteins in inducing a protective immune response compared with the results of immunization with inactivated JEV vaccine. Some near-line hybrid and distant crosses that are immunized with the protein encoding the JEV membrane protein (PE) are highly protective against lethal JEV attacks with similar protective effects as those obtained with inactivated vaccines. However all of them