系统性红斑狼疮(SLE)是以多器官损害症状为临床表现的慢性系统性自身免疫性疾病之一,其早期死亡的主要原因为疾病本身的活动和感染。随着SLE患者生存时间的延长,早发动脉粥样硬化(ath-erosclerosis,AS)的趋势日显突出。流行病学研究发 Systemic lupus erythematosus (SLE) is one of the chronic systemic autoimmune diseases that are clinically manifested by symptoms of multiple organ damage. The main cause of early death is the activity and infection of the disease itself. With the prolongation of the survival time of SLE patients, the trend of early onset atherosclerosis (AS) is increasingly prominent. Epidemiological research and development