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目的：了解抑郁症患者中展开细致化干预措施的临床有效性。方法：随机抽选出123例因患抑郁症、于2014年12月-2016年12月间入院的患者，随机分组：60例Ⅰ组病例临床干预工作中展开一般干预，63例Ⅱ组则展开细致化干预，给予两组病例的心理状态与治疗效能感等客观比较。结果：展开专业干预措施后，60例Ⅰ组GSES表计（21.78±6.22）分，63例Ⅱ组为（29.67±5.86）分，（P＜0.05），同时Ⅱ组SDS表计分比Ⅰ组低，（P＜0.05）。结论：将细致化干预措施充分应用至抑郁症患者中，可使其心理状态进一步改善，从而促进转归。“,”Objective:Understanding of depression in patients with a detailed clinical efectiveness of intervention measures.Methods:Randomly selected123 patients with depression, in December2014 - December2016 hospitalized patients with random grouping:60 casesⅠ group in clinical intervention work general intervention,63 cases ofⅡ detailed intervention group, give two groups of cases the psychological status and treatment of self-efcacy and other objective comparison. Results:Afer a professional intervention,60 casesⅠ group GSES meter (21.78-6.22), (29.67-5.86) for63 cases ofⅡ group, (P <0.05), while lowⅡ SDS score table thanⅠ group, (P <0.05).Conclusion:Detailed intervention measures apply to depression patients, can make its further improve mental state, thus promote the outcome.