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目的探讨联合检查在子宫内膜异位症中的临床价值。方法对为子宫内膜异位症患者30例、术前用放射免疫法测定CA125,并用酶免疫吸附法测定子宫内膜异位抗体水平。结果子宫内膜异位症组血清CA125水平为(79±40)U/ml,高于对照组(22±11)u/ml、子宫内膜异位症组子宫内膜异位抗体阳性率为55%,对照组为10%。单项测定CA125诊断子宫内膜异位症的敏感性为75%,特异性为83%;单项测定子宫内膜异位抗体诊断子宫内膜异位症的敏感性为55%,特异性为90%;如以两者均阳性为诊断标准,测敏感性为48%,特异性为100%;如以其中之一阳性为诊断标准,敏感性为82%,特异性为73%。结论测定CA125、子宫内膜异位抗体水平对子宫内膜异位症有较好的辅助诊断价值,联合测定更能提高诊断的正确性。
Objective To investigate the clinical value of combined examination in endometriosis. Methods 30 cases of endometriosis patients, preoperative determination of CA125 by radioimmunoassay, and enzyme-linked immunosorbent assay for endometriosis antibody levels. Results The serum level of CA125 in endometriosis group was (79 ± 40) U / ml, higher than that in control group (22 ± 11) u / ml. The positive rate of endometriosis antibody in endometriosis group was 55% in the control group and 10% in the control group. The sensitivity and specificity of CA125 in the diagnosis of endometriosis were 75% and 83%, respectively. The sensitivity and specificity of single assay of endometriosis in diagnosing endometriosis were 55% and 90% ; If both are positive diagnostic criteria, the sensitivity of 48%, specificity of 100%; as one of the positive diagnostic criteria, the sensitivity was 82%, the specificity was 73%. Conclusion The determination of CA125, endometriosis antibody levels of endometriosis has a better diagnostic value, the joint determination can improve the diagnostic accuracy.