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作者采用以安慰剂为对照的双盲法比较了小儿急性中耳炎的青霉素2日疗法和7日疗法,即用青霉素V 55mg/kg/天,7日疗法组每日给青霉素2次,持续7日;2日疗法组头两日和前者一样,每日给青霉素2次,共4次,以后5日不给青霉素而给安慰剂,给药时间和次数不变。本组能够进行分析的1～10岁的急性中耳炎患儿共95例,7日疗法组49例,2日疗法组46例。在治疗过程中和疗程结束时根据耳痛等症状,发烧情况,普通感冒症状,耳镜下鼓膜所见以及鼓室测压结果,对上述两组进行了比较,凡一天后病儿未因疼痛而啼哭、不需服止痛药、2日后无中耳炎症状、耳流脓不到6天、一周内对侧不发炎
The authors compared the placebo-controlled double-blind method of penicillin in children with acute otitis media on the 2nd and seventh days of treatment, penicillin V 55mg / kg / day, 7 day treatment group penicillin twice daily for 7 days On the 2nd day of the treatment group, the first two days were the same as the former, giving penicillin twice a day for 4 times, but not giving penicillin on the 5th after giving placebo. The time and number of administration were unchanged. A total of 95 children with acute otitis media from 1 to 10 years old were analyzed in this group. 49 cases were treated on the 7th day and 46 cases were treated on the 2nd day. During the course of treatment and at the end of treatment, the above two groups were compared on the basis of the symptoms such as earache and fever, the common cold symptom, the tympanic membrane under the otoscope and the tympanometry, Crying, without taking painkillers, no symptoms of otitis media after 2 days, purulent ear less than 6 days, contralateral non-inflamed within a week