1985年11月,美国科罗拉多州输血中心用酶联免疫吸附试验和斑点采志试验,发现1位供血员的血清HTLV-Ⅲ/LAV 抗体阳性。早在1985年4月和8月他就在这个中心献过血,当时血清学检查阴性.4月份献出的血输给了两个人均未发现异常。8月份献出的血也输给了两个人,其中1人没有其他感染 HTLV-Ⅲ/LAV 的危险因素,而后来却发现血清抗体阳性。这是美国血库和血浆中心开始对献血者进行常规筛选试验后所发生的首例传染病例. In 1985 November, Colorado transfusion center using enzyme-linked immunosorbent assay and blotch test, and found that one of the blood donors serum HTLV-III / LAV antibody positive. He had blood donated at this center as early as April and August 1985, when serological tests were negative, and the blood donated in April gave no sign of abnormalities to both individuals. Blood donated in August was also lost to two individuals, one of whom had no other risk of contracting HTLV-III / LAV but later found to be seropositive. This is the first case of infection that has occurred since the U.S. Blood Bank and Plasma Center began routine screening tests of blood donors.