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目的调查本地区人博卡病毒母婴感染情况。方法用ELISA检测母婴血清人博卡病毒IgG抗体及用荧光定量PCR检测母婴血清人博卡病毒DNA。结果316例母婴配对标本中,孕妇血清人博卡病毒IgG抗体阳性的有127例,阳性率为40.20%(127/316);新生儿脐带血人博卡病毒IgG抗体阳性有93例,阳性率为29.43%(93/316)。新生儿人博卡病毒IgG抗体阳性占母亲人博卡病毒IgG抗体阳性的百分比为73.23%(93/127)。母婴同时人博卡病毒IgG抗体阳性为93例。316例母婴配对标本人博卡病毒DNA均为阴性。结论人博卡病毒IgG抗体可从孕妇经胎盘传给新生儿,但是否存在人博卡病毒母婴垂直传播尚有待于进一步研究。
Objective To investigate the prevalence of mother-infant Boca virus in this area. Methods The maternal and fetal serum bocavirus IgG antibodies were detected by ELISA and the maternal and fetal serum human bocavirus DNA by fluorescence quantitative PCR. Results Of the 316 maternal and infant paired samples, there were 127 positive cases of pregnant women with bocavirus IgG antibody, the positive rate was 40.20% (127/316). There were 93 positive cases of cord blood Bocavirus IgG antibody in neonates The rate was 29.43% (93/316). The positive percentage of neonatal Bocaviruses positive for IgG antibodies to bocavirus was 73.23% (93/127). The same time, mother and baby bocavirus IgG antibody was 93 cases. 316 cases of maternal and infant paired specimens of human Boka virus DNA were negative. Conclusions Human Bocavirus IgG antibody can be transmitted from placenta to newborn from pregnant women. However, whether there is vertical transmission of mother-infant Bocavirus remains to be further studied.