重症急性胰腺炎 (severeacutepancreatitis ,SAP)以病情危重、临床表现复杂、进展迅速、死亡率高等特点引起广大临床工作者和专家学者的重视。其治疗观点 ,经历了几次大更替 ,一直是医学界争论不休的问题。 2 0世纪 90年代以后 ,随着对SAP的机制、病理生理的深入了解和循证医学 Severe acute pancreatitis (severe acutepancreatitis, SAP) to critically ill patients, clinical manifestations of complex, rapid progress, high mortality caused by the majority of clinicians and experts and scholars attention. The treatment point of view, has undergone several major changes, has been the endless debate in the medical profession. After the 1990s, with the understanding of SAP’s mechanism, pathophysiology and evidence-based medicine