目的:探讨MODS发病的中西医临床高危因素。方法:通过对45例MODS患者的回顾研究,分析存活组和死亡组MODS的急性生理与慢性健康评估(APACHEⅡ)评分、脏衰发生率及数量及中医证型等危险因素之间关系。结果:存活组与死亡组在APACHEⅡ评分、年龄、多形核粒细胞数量和脏衰发生率方面有显著差异(p<0.05),存活组毒邪、热邪蕴结占62%,气虚占53%,死亡组毒邪,热邪蕴结占65%、气虚占71%。结论:APACHEⅡ评分、年龄、多形核粒细胞数量、脏衰率及脏衰数对MODS有较好临床评价作用。在MODS患者以毒邪、热邪蕴结证和气虚证为主。 Objective: To investigate the clinical risk factors of MODS in Chinese and Western medicine. Methods: A retrospective study of 45 patients with MODS was conducted to analyze the relationship between acute physiology and chronic health assessment (APACHEⅡ) scores, incidence and quantity of dirty decay, TCM syndromes and other risk factors in survivors and death patients. Results: There were significant differences (P <0.05) between APACHEⅡscore, age, polymorphonuclear neutrophil count and incidence of visceral failure in survival group and death group %, Death group toxins, heat Xie Yun 65%, Qi 71%. Conclusion: APACHE Ⅱ score, age, polymorphonuclear neutrophil number, dirty and bad decay rate of MODS have a better clinical evaluation. In MODS patients to poison evil, heat evil accumulate card and qi deficiency-based.