老年急性脑梗死患者的氧化低密度脂蛋白与颈动脉粥样硬化斑块的关系

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目的:探讨老年急性脑梗死患者血浆内的氧化低密度脂蛋白与颈动脉粥样硬化斑块的关系。方法:选取我院2012年1月~2013年3月收治的急性脑梗死老年患者65例,依照颈动脉超声的结果将患者分为两组,对照组9例患者均未发现粥样硬化斑块,观察组56例患者存在斑块,再依据患者情况分为观察A组42例(不稳定斑块)与观察B组14例(稳定斑块),对所有患者的氧化低密度脂蛋白情况进行检测,并开展比较与分析。结果:通过检验得出结果,存在颈动脉斑块的观察组的氧化低密度脂蛋白显著高于未见颈动脉斑块的对照组,组间差异明显具有统计学意义( P<0.05);不稳定斑块的观察A组的氧化低密度脂蛋白显著高于稳定斑块的观察B组,组间差异显著具有统计学意义( P<0.05)。结论:老年急性脑梗死患者的氧化低密度脂蛋白与颈动脉粥样硬化斑块具有密切的联系,前者可明确的判断后者的稳定程度,是临床诊断老年患者发病的有效手段。“,”Objective:To study the relationship between plasma oxidized low density lipoproteinand carotid atherosclerotic plaque in elderly patients with acute cerebral infarction. Methods:Our hospital in January 2012 ~ March 2013 were treated 65 cases of elderly patients with acute cerebral infarction. According to the results of carotid ultrasound patients were divided into two groups. Nine patients in the control group were not found in atherosclerotic plaques, the presence of plaque in the observation group 56 patients. And then based onobservation of patients were divided into observation group A, 42 patients (unstable plaque) and the observation group B 14 patients (stable plaques). Detection of oxidized LDL in patients of al ,and conduct comparison and analysis. Result:The results obtained by testing is the presence of carotid plaque oxidized LDL was significantly higher than no carotid artery plaque, unstable plaque oxidized LDL was significantly higher than stable plaque, Significantly between the two groups was statistical y significant difference (P <0.05). Conclusion: Elderly patients with acute cerebral infarction oxidized LDL and carotid atherosclerotic plaques with close relationship.The former can be clearly judge of the stability of the latter, elderly patients with clinical diagnosis of onset is an effective means.
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