目的探讨脾窦岸细胞血管瘤(LCA)的临床与病理学特征、诊断与鉴别诊断。方法对3例脾窦岸细胞血管瘤进行临床与病理学观察,并复习相关文献。结果患者CT增强扫描提示动脉期及门静脉期脾内有多发性、大小不一的无明显强化低密度影,境界清楚,延迟期病灶部分强化,密度与正常脾组织相似。组织学特点为肿瘤由互相吻合的腔隙组成,部分区域呈乳头状结构,瘤细胞呈柱状或立方形,细胞无明显异型,内皮细胞及组织细胞标记均呈阳性。例2伴有食管小细胞癌。结论脾LCA是一种罕见的脾血管源性肿瘤,其诊断主要依靠病理组织学及免疫组化标记,CT增强扫描可能有助于诊断。由于该肿瘤常伴发内脏恶性肿瘤,对此类患者应进行仔细检查及密切随访。 Objective To investigate the clinical and pathological features, diagnosis and differential diagnosis of LCA in splenic sinusoid. Methods Three cases of splenic sinus hemangiomas were observed clinically and pathologically, and the related literatures were reviewed. Results CT enhanced CT scan showed multiple splenic stages in the arterial phase and portal vein phase. There was no obvious enhancement of low-density shadow in different sizes. The clear-cut state of the lesion was partially enhanced and the density was similar to normal spleen tissue. Histological features of the tumor by the lacunar coincide with each other, part of the area was papillary, tumor cells were columnar or cubic, the cells showed no abnormalities, endothelial cells and tissue cells were positive. Case 2 with esophageal small cell carcinoma. Conclusions Splenic LCA is a rare splenic angiogenic tumor. The diagnosis of splenic LCA mainly depends on histopathology and immunohistochemical markers. CT enhanced scan may be helpful for diagnosis. As the tumor often associated with visceral malignancy, such patients should be carefully examined and followed up closely.