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近年来,由于铅在作业环境中含量日趋降低,明显重症的职业性铅中毒已属少见。而长期低浓度铅暴露对机体早期影响的研究,已引起国内外学者的普遍重视。本文仅就这方面的有关文献作一综述。 一、铅对血液系统的影响 一般认为卟啉代谢紊乱是铅对机体影响的较早的重要变化之一,其中尿粪卟啉检验应用较早,但文献报道,在低浓度铅暴露下此项检验很不敏感。 Alesslo等曾对108名铅接触者进行血铅和红细胞原卟啉(EPP)测定,结果二
In recent years, due to the decreasing content of lead in the operating environment, obviously severe occupational lead poisoning is rare. The long-term low concentration of lead exposure to the body early impact study has attracted widespread attention of scholars at home and abroad. This article only reviews the relevant literature in this area. First, the impact of lead on the blood system It is generally believed that the disorder of porphyrin metabolism is one of the earliest important changes in the impact of lead on the body, of which urinary excretion of porphyrin test earlier, but the literature reports, exposed to low concentrations of lead Test is very insensitive. Alesslo et al had 108 lead exposure to blood lead and erythrocyte protoporphyrin (EPP) determination, the results of two