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近年来,我科应用α-干扰素预防尖锐湿疣复发获得较好效果,现报告如下。 1.资料和方法 病例均为我院病人,共60例,均为男性。年龄18～60岁,平均29.5岁。病程1周～半年,平均23月,均为临床表现典型,经5％醋酸溶液涂布证实尖锐湿疣,皮疹数目为1～数10个。平均6.23个。皮损分布冠状沟,包皮内板,阴茎体。皮损形态似乳头状和菜花样。 所有患者以前均未接受任何治疗,无肝、肾、心血管疾病,对足叶草脂毒素酊和α-干扰素不过敏。试验方法:全部病人采用疣脱欣(辽宁华卫制药股份有限公司)外搽干疣体。待疣体全部脱落,醋酸白试验(-),然后随机分2组,甲组行局部病灶皮下浸润注射干扰素10万u(北京四环生物生化药厂)加1％普鲁卡因2ml;乙组拟病毒唑0.1g(广州市桥药厂)加1％普鲁卡因2ml行局部病灶皮下浸润注射,使药物均匀分布。每周治疗2次,每次相隔3天。共治疗2周,总计4次。治疗后随访
In recent years, our department applied α-interferon to prevent recurrence of genital warts get better results are as follows. 1. Materials and Methods Patients were hospital patients, a total of 60 cases, all men. Age 18 to 60 years old, average 29.5 years old. Duration of 1 week ~ 6 months, an average of 23 months, are typical clinical manifestations, 5% acetic acid solution coated confirmed condyloma, the number of rash is 1 to several 10. Average 6.23. Coronal distribution of lesions, foreskin plate, penis body. Skin lesions like papillary and cauliflower pattern. None of the patients had previously received any treatment and had no liver, kidney, or cardiovascular disease. They were not allergic to footpadolin tincture and interferon alpha. Test Methods: All patients with wart off Xin (Liaoning Hua Wei Pharmaceutical Co., Ltd.) Waicha dry wart body. When all the warts were shed, white acetic acid test (-) was performed and divided randomly into two groups. Group A was subcutaneously infiltrated with subcutaneous infiltration of interferon 100 000 u (Beijing Sihuan Biochemical Pharmaceutical Factory) plus 1% procaine 2 ml; Group B Ribavirin 0.1g (Guangzhou Bridge Pharmaceutical Factory) plus 1% procaine 2ml local subcutaneous injection of subcutaneous injection, the drug evenly distributed. Treatment 2 times a week, every 3 days apart. A total of 2 weeks treatment, a total of 4 times. Follow-up after treatment