自诺氟沙星(一译氟哌酸,Norfloxacin)被研制出来后,新喹诺酮药物这一用语便逐渐被固定下来。1986年第34届日本化学疗法学会总会以“新喹诺酮类药物的临床应用及展望”为题举行了专题讨论会。对该类药物的开发过程、抗菌作用机制、吸收、排泄、体内分布及临床应用作了论述。其后,新喹诺酮类药物的使用便飞跃性地增大,新改进的该类药物不断被研制出来,并应用于临床。 After the development of norfloxacin (Norfloxacin), the term new quinolone was gradually fixed. In 1986 the 34th Japan Society of Chemotherapy Society held a symposium titled “Clinical Application and Prospect of New Quinolones”. The development of such drugs, antibacterial mechanism, absorption, excretion, distribution in vivo and clinical applications were discussed. Since then, the use of new quinolones has dramatically increased, and new and improved drugs have been developed and used clinically.