对 6 2例不明原因胸腔积液患者进行纤维支气管镜检查 ,并检测胸水腺苷脱氨酶、癌胚抗原及血清癌胚抗原。结果显示 6 2例不明原因胸腔积液患者中 ,经纤维支气管镜检查及活检病理诊断肺部肿瘤 2 9例 ;结核性胸膜炎及活检病理诊断肺部肿瘤 2 9例 ;结核性胸膜炎患者胸水腺苷脱氨酶明显高于肺癌患者和其他组患者(P <0 .0 1) ;肺癌患者胸水、血清癌胚抗原显著高于良性肺病患者 (P <0 .0 1)。纤维支气管镜检查并胸水腺苷脱氨酶、癌胚抗原测定是诊断不明原因胸腔积液有效的辅助方法 Sixty-two patients with unexplained pleural effusion were examined by fiberoptic bronchoscopy, and adenosine deaminase, carcinoembryonic antigen and serum carcinoembryonic antigen were detected. The results showed that 26 cases of pleural effusion in patients with unexplained pleural effusion bronchoscopy and biopsy pathological diagnosis of 29 cases of lung cancer; tuberculous pleurisy and biopsy pathological diagnosis of 29 cases of lung cancer; pleural effusion in patients with pleural effusion adenosine Deaminase was significantly higher in patients with lung cancer and other patients (P <0.01). The levels of pleural effusion and serum carcinoembryonic antigen in patients with lung cancer were significantly higher than those in patients with benign lung disease (P <0.01). Fiberoptic bronchoscopy and pleural effusion adenosine deaminase, carcinoembryonic antigen assay is an effective adjunct to diagnosis of unexplained pleural effusion