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本文研究了选择性β_1受体阻滞剂美托洛尔(metoprolol)治疗多源性房性心动过速(MAT)的效能。 11例伴有严重肺部疾病的MAT患者,均有缺O_2、高碳酸、酸中毒以及电解质紊乱情况,用药前作了纠正。所有患者用戊脉安、心得安和苯妥英钠治疗后MAT均未得到明显纠正。在用本品之前,平均房率为每分钟142.3±17.2次,平均室率每分钟131.4±24.3次。口服给予本品25~50 mg,3小时后所有患者的MAT都恢复了窦性节律,平均室率为每分钟86.9±6.8次(p<0.01)。用
This article investigates the efficacy of metoprolol, a selective beta-1 blocker, in the treatment of multi-source atrial tachycardia (MAT). MAT patients with severe pulmonary disease in 11 cases, all lack O_2, hypercapnia, acidosis and electrolyte imbalance, corrected before treatment. All patients with verapamil, propranolol and phenytoin sodium MAT after treatment were not significantly corrected. Before using this product, the average room rate of 142.3 ± 17.2 times per minute, the average room rate of 131.4 ± 24.3 times per minute. Oral administration of this product 25 ~ 50 mg, MAT in all patients after 3 hours to restore sinus rhythm, the average room rate was 86.9 ± 6.8 times per minute (p <0.01). use