运动神经元病 (motorneurondisease ,MND)是病因不明 ,选择性地损害脊髓前角、桥、延脑神经运动核和锥体束为主的一组慢性进行性变性疾病 ,致残率极高 ,发病率约 (1～ 6 ) / 10万。该病起病隐匿 ,进展缓慢 ,误诊率可达 4 0 % [1] 。本文就国内外MND的治疗进展综述如下。1　抗兴 Motor neuron disease (MND) is a group of chronic progressive degenerative diseases with unknown etiology and selective damage to the anterior horn of the spinal cord, the bridge, the motor nucleus of the medulla oblongata and the pyramidal tract, with a high morbidity and morbidity Rate of about (1 ~ 6) / 100,000. The disease occult onset, slow progress, misdiagnosis rate of up to 40% [1]. This article reviews the progress of MND treatment at home and abroad as follows. 1 anti-Xing