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近年来,随着应激性溃疡发病率的上升,胃粘膜血流量的测定引起临床科研工作者的普遍重视。胃粘膜血流不仅在胃酸分泌中起着重要作用,更是左右胃粘膜防御功能的主要因素。各种测定方法已陆续应用于实验工作中,包括人及动物模型。使用这些方法就能进一步认识胃牯膜血流在防御急性胃粘膜损伤中的作用。本文着重综述现今对胃粘膜血流和防御机制的认识和各种测定粘膜血流方法及其优缺点,以便外科工作者概括了解这个领域。
In recent years, with the increased incidence of stress ulcer, the determination of gastric mucosal blood flow caused widespread concern of clinical scientists. Gastric mucosal blood flow not only plays an important role in gastric acid secretion, but also is the main factor in the function of gastric mucosal defense. A variety of measurement methods have been gradually applied to experimental work, including human and animal models. Using these methods, we can further understand the role of gastric lavage in preventing acute gastric mucosal injury. This article focuses on current understanding of gastric mucosal blood flow and defense mechanisms and various methods of determining mucosal blood flow and its advantages and disadvantages so that surgeons can get an overview of the field.