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肿瘤的细胞因子基因治疗研究内容和临床试用项目占肿瘤基因治疗之首,根据应用途径和原理不同,可将其分为五种类型,本文介绍了这五种类型的细胞因子基因治疗的原理及其抗肿瘤效果,尤其是对细胞因子基因转染瘤苗的作用机制及影响因素进行了较详尽的综述。
The contents of tumor gene therapy and clinical trials for tumors account for the first place in tumor gene therapy. According to different application methods and principles, they can be divided into five types. This paper describes the principles of these five types of cytokine gene therapy and The anti-tumor effect, especially the mechanism of action of cytokine gene transfected tumor vaccine and its influencing factors were reviewed in detail.