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目的探讨正天丸联合尼莫地平治疗血管神经性头痛的临床效果。方法选取河南煤化集团鹤煤公司总医院内科2011年10月—2013年10月收治的103例血管神经性头痛住院和门诊患者,采用随机数字表法分为对照组51例和观察组52例。对照组给予尼莫地平片治疗,观察组加用正天丸治疗,连续治疗30d,观察患者临床症状改善情况、综合疗效和不良反应发生情况。结果两组患者治疗前头痛症状评分比较,差异无统计学意义(P>0.05);治疗后观察组头痛症状评分均低于对照组,差异有统计学意义(P<0.01)。观察组总有效率(92.31%)高于对照组(76.47%),差异有统计学意义(P<0.05)。结论正天丸联合尼莫地平治疗血管神经性头痛效果确切,能够充分结合现代医学与传统医学优势,通过抑制平滑肌收缩、疏风活血通络和养血平肝等理论改善临床症状,在提高生存质量和改善预后等方面具有积极作用。
Objective To investigate the clinical effect of Zhengtian pill combined with nimodipine in the treatment of vascular neuropathic headache. Methods A total of 103 inpatients and outpatients with vascular neuropathic headache admitted from October 2011 to October 2013 in Hebi Coal General Hospital of Henan Coal Group were divided into control group (n = 51) and observation group (n = 52) by random number table. The control group was treated with nimodipine. The observation group was treated with Zhengtian Pill. The rats in the observation group were continuously treated for 30 days. The improvement of clinical symptoms, the comprehensive curative effect and the adverse reactions were observed. Results There was no significant difference in headache symptom scores between the two groups before treatment (P> 0.05). After treatment, the headache symptom scores in the observation group were lower than those in the control group (P <0.01). The total effective rate (92.31%) in the observation group was higher than that in the control group (76.47%), the difference was statistically significant (P <0.05). Conclusion Zhengtian pills combined with nimodipine have the exact effect of treating vascular neuropathic headache and can fully combine the advantages of modern medicine and traditional medicine to improve the clinical symptoms by inhibiting the contraction of smooth muscle, invigorating the circulation and promoting blood circulation, and nourishing the liver and improving the survival Quality and improve prognosis and other aspects have a positive effect.