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观察伐昔洛韦与卡介菌多糖核酸联合治疗带状疱疹伴神经痛的临床疗效及安全性。对86例发病早期的带状疱疹患者随机分为3组进行治疗,其中A组(伐昔洛韦、联合卡介菌多糖核酸组)35例;B组(阿昔洛韦、联合卡介菌多糖核酸组)27例;C组(伐昔洛韦组)24例。A组治疗后皮损愈合时间明显缩短,疼痛持续时间也明显缩短,带状疱疹后遗神经痛(PNH)发生率下降。伐昔洛韦联合卡介菌多糖核酸治疗带状疱疹伴神经痛,可提高临床疗效、缩短病程、降低后遗神经痛发生率。
To observe the clinical efficacy and safety of valaciclovir and BCG polysaccharide nucleic acid in the treatment of herpes zoster with neuralgia. Eighty-six patients with early onset herpes zoster were randomly divided into three groups: 35 patients in group A (valacyclovir combined with BCG-PSN), group B (acyclovir in combination with BCG Polysaccharides nucleic acid group) 27 cases; C group (valacyclovir group) 24 cases. A group of skin lesions after treatment significantly shorter healing time, pain duration was significantly shorter, the incidence of postherpetic neuralgia (PNH) decreased. Valaciclovir combined with BCG polysaccharide nucleic acid in the treatment of shingles with neuralgia can improve clinical efficacy, shorten the course of disease and reduce the incidence of post-natal neuralgia.