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目的探讨降钙素原(PCT)联合C反应蛋白(CRP)、血培养检测在新生儿败血症中的临床价值,为新生儿败血症的早期诊断和治疗提供依据。方法选取2009年1月至2013年12月在我科住院治疗的50名新生儿败血症患儿为研究组,同期住院的50例非感染患儿为对照组,对比两组新生儿的PCT、CRP和血培养的变化。结果研究组患儿的PCT、CRP结果明显高于非感染组,差异有统计学意义(P<0.05),且PCT的敏感性和特异性高于CPP。结论 PCT在研究组早期即可升高,且敏感性和特异性均高于CRP,可作为新生儿败血症早期检测指标。
Objective To investigate the clinical value of procalcitonin (PCT) combined with C-reactive protein (CRP) and blood culture in the detection of neonatal sepsis, and to provide evidence for the early diagnosis and treatment of neonatal sepsis. Methods Fifty newborn infants with sepsis treated in our department from January 2009 to December 2013 were selected as study group and 50 hospitalized non-infected children as control group. The PCT, CRP And blood culture changes. Results The PCT and CRP results of study group were significantly higher than those of non-infected group (P <0.05), and the sensitivity and specificity of PCT were higher than that of CPP. Conclusion PCT increased in the early stage of the study group, and the sensitivity and specificity were higher than the CRP, can be used as an early detection index of neonatal sepsis.